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Mayland Chang Selected Research

Cyclopropanes

1/2019Combined Scaffold Evaluation and Systems-Level Transcriptome-Based Analysis for Accelerated Lead Optimization Reveals Ribosomal Targeting Spirooxindole Cyclopropanes.

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Mayland Chang Research Topics

Disease

19Neoplasms (Cancer)
01/2022 - 05/2005
18Infections
05/2023 - 10/2013
11Wounds and Injuries (Trauma)
01/2022 - 01/2014
9Neoplasm Metastasis (Metastasis)
10/2018 - 05/2005
7Stroke (Strokes)
01/2018 - 11/2007
6Inflammation (Inflammations)
02/2021 - 02/2011
5Ulcer
01/2022 - 01/2016
4Diabetic Foot
01/2020 - 01/2016
4Spinal Cord Injuries (Spinal Cord Injury)
11/2017 - 04/2011
4Traumatic Brain Injuries (Traumatic Brain Injury)
11/2017 - 01/2013
2Dysbiosis
10/2023 - 06/2021
2Melanoma (Melanoma, Malignant)
11/2020 - 11/2016
2Infarction (Infarctions)
05/2018 - 05/2012
2Brain Ischemia (Cerebral Ischemia)
05/2018 - 05/2012
2Gliosis
01/2013 - 04/2011
2Cardiovascular Diseases (Cardiovascular Disease)
02/2011 - 12/2009
1Rare Diseases (Rare Disease)
08/2022
1Idiopathic Pulmonary Fibrosis
08/2022
1Pterygium
08/2022
1Fibrosis (Cirrhosis)
08/2022
1Pressure Ulcer (Bedsore)
01/2022
1Suppuration
01/2022
1Neuromyelitis Optica (Devic's Disease)
01/2021
1Sarcoma (Soft Tissue Sarcoma)
11/2020
1Disease Progression
11/2020
1Bacterial Infections (Bacterial Infection)
11/2020
1Diarrhea
11/2020
1Hypoxia (Hypoxemia)
01/2020
1Pancreatic Neoplasms (Pancreatic Cancer)
10/2018
1Cerebral Infarction
05/2018
1Cerebral Hemorrhage
05/2018
1Ischemic Stroke
05/2018
1Body Weight (Weight, Body)
01/2018
1Virus Diseases (Viral Diseases)
11/2017
1Brain Injuries (Brain Injury)
01/2015
1Community-Acquired Infections
10/2014
1Acinetobacter Infections
09/2013
1Mitochondrial Diseases (Mitochondrial Disease)
01/2013
1Subarachnoid Hemorrhage (Aneurysmal Subarachnoid Hemorrhage)
10/2012
1Hypertension (High Blood Pressure)
09/2012

Drug/Important Bio-Agent (IBA)

27Matrix Metalloproteinases (MMPs)IBA
08/2022 - 05/2005
15Anti-Bacterial Agents (Antibiotics)IBA
10/2023 - 10/2013
14GelatinasesIBA
05/2018 - 05/2005
13SB 3CT compoundIBA
05/2018 - 05/2005
10Matrix Metalloproteinase InhibitorsIBA
05/2019 - 05/2005
7Peptide Hydrolases (Proteases)FDA Link
01/2021 - 04/2011
5Matrix Metalloproteinase 9 (Gelatinase B)IBA
01/2020 - 08/2008
4(R)-ND-336IBA
08/2022 - 01/2021
4Linezolid (Zyvox)FDA Link
02/2021 - 03/2014
4LactamsIBA
01/2016 - 10/2013
4EnzymesIBA
12/2015 - 08/2008
3Matrix Metalloproteinase 14 (MT1-MMP)IBA
01/2022 - 11/2016
3Reactive Oxygen Species (Oxygen Radicals)IBA
01/2021 - 01/2016
3VancomycinFDA LinkGeneric
11/2020 - 03/2014
3OxadiazolesIBA
03/2020 - 03/2014
3ethylene sulfide (thiirane)IBA
11/2016 - 10/2011
2Oxygen (Dioxygen)IBA
08/2022 - 05/2018
2Proteins (Proteins, Gene)FDA Link
08/2022 - 11/2020
2Small Interfering RNA (siRNA)IBA
01/2022 - 11/2020
2Tazobactam Drug Combination Piperacillin (Zosyn)FDA LinkGeneric
01/2020 - 11/2015
2Matrix Metalloproteinase 2 (Gelatinase A)IBA
10/2013 - 04/2011
2Doxycycline (Periostat)FDA LinkGeneric
09/2012 - 09/2009
1MacrolidesIBA
05/2023
13- (formylhydroxyamino)- 2- (3- phenyl- 1- propyl)butanoic acid (2,2- dimethyl- 1- methylcarbamoyl- 1- propyl)amideIBA
08/2022
1CollagenIBA
08/2022
1AutoantibodiesIBA
01/2021
1Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
01/2021
1Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
01/2021
1RNA (Ribonucleic Acid)IBA
11/2020
1Collagenases (Collagenase)FDA Link
11/2020
1Interleukin-6 (Interleukin 6)IBA
06/2020
1Blood Proteins (Serum Proteins)IBA
03/2020
1Enzyme Precursors (Zymogens)IBA
01/2020
1LuminolIBA
01/2020
1batimastat (BB 94)IBA
05/2019
1Drug CombinationsIBA
01/2019
1spirooxindoleIBA
01/2019
1CyclopropanesIBA
01/2019
1Interleukin-33IBA
10/2018
1laminin AIBA
10/2018
1Peptides (Polypeptides)IBA
09/2018
1Angiotensin IIIBA
09/2018
1aclerastideIBA
09/2018
1Tissue Plasminogen Activator (Alteplase)FDA Link
05/2018
1DP 460IBA
01/2018
1ND 322IBA
11/2016
1QuinazolinonesIBA
01/2016
1Oxacillin (Prostaphlin)FDA LinkGeneric
01/2016
1Meropenem (Merrem)FDA LinkGeneric
11/2015
1Penicillin-Binding Proteins (Penicillin-Binding Protein)IBA
07/2014
1CeftarolineFDA Link
07/2014
1Urea (Carbamide)FDA LinkGeneric
10/2013
1CarbamatesIBA
10/2013
1Carbapenems (Carbapenem Antibiotics)IBA
09/2013
1Minocycline (Cyclops)FDA LinkGeneric
09/2012

Therapy/Procedure

5Surgical Amputation (Amputations)
01/2022 - 12/2015
4Therapeutics
01/2023 - 05/2012
1Oral Administration
06/2021
1Drug Therapy (Chemotherapy)
11/2020
1Topical Administration
12/2015